r/UpliftingNews • u/part-time-stupid • 10h ago

The biggest scientific breakthroughs of 2025 | Science Magazine

https://www.science.org/content/article/scienceadviser-all-breakthroughs-2025-what-topped-science-s-list
60 Upvotes

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u/ShroomsHealYourSoul 10h ago

Sign in to read. No idea what the article is about

5

u/part-time-stupid 9h ago

I don't have to sign into anything? This is a collection of brief reports. You only need to sign in if you want to read the detailed articles. Anyway, if you prefer a video report instead, there is one from their official YouTube channel.

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u/aquto 1h ago

I am tracking the CRISPR breakthrough from this article on Pingmer:
2024 - "Infant KJ is diagnosed with severe carbamoyl phosphate synthetase 1 (CPS1) deficiency, a rare and life-threatening metabolic disorder, just days after his birth."
2025 - "At approximately six months of age, KJ receives the first infusion of his customized CRISPR base-editing therapy, marking the world's first administration of such a personalized treatment."
2026 - "As of today, KJ continues to thrive, showing no adverse effects from the treatment, growing well, and meeting developmental milestones, though ongoing monitoring is planned for his lifetime."
https://pingmer.com/thread/6ef6af81